Functional Genomics Approaches to Elucidate Vulnerabilities of Intrinsic and Acquired Chemotherapy Resistance

Drug resistance is a commonly unavoidable consequence of cancer treatment that results in therapy failure and disease relapse. Intrinsic (pre-existing) or acquired resistance mechanisms can be drug-specific or be applicable to multiple drugs, resulting in multidrug resistance. The presence of drug r...

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Bibliographic Details

Published in:	Cells
Main Authors:	Ronay Cetin, Eva Quandt, Manuel Kaulich
Format:	Article
Language:	English
Published:	MDPI AG 2021-01-01
Subjects:	chemotherapy resistance cancer and drug vulnerabilities functional genomics RNAi and CRISPR screens
Online Access:	https://www.mdpi.com/2073-4409/10/2/260