Obesity and Breast Cancer: Interaction or Interference with the Response to Therapy?

Background: Aromatase inhibitors (AI) are widely used for treating hormone-sensitive breast cancer (BC). Obesity, however, due to aromatase-mediated androgen conversion into estradiol in the peripheral adipose tissue, might impair AI inhibitory capacity. We aimed at identifying a cut-off of body mas...

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Bibliographic Details
Published in:Current Oncology
Main Authors: Silvia Riondino, Vincenzo Formica, Elena Valenzi, Cristina Morelli, Valeria Flaminio, Ilaria Portarena, Francesco Torino, Mario Roselli
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Subjects:
Online Access:https://www.mdpi.com/1718-7729/30/1/94