Anti-Hyperalgesic Effect of Isopulegol Involves GABA and NMDA Receptors in a Paclitaxel-Induced Neuropathic Pain Model

<b>Background</b>: Neuropathic pain can be triggered by chemotherapy drugs such as paclitaxel (PTX). Management of pain is limited by drugs’ ineffectiveness and adverse effects. Isopulegol (ISO) is a monoterpene present in the essential oils of several aromatic plants and has promising p...

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Bibliographic Details

Published in:	Pharmaceuticals
Main Authors:	Deyna Martins, Boris Acha, Mickael Cavalcante, Suellen Pereira, Ana Viana, Flaviano Ribeiro Pinheiro-Neto, Priscyla Mendes, Dalton Dittz-Júnior, Francisco Oliveira, Tatiana Ventura, Maria da Graça Lobo, Fátima Ferreirinha, Paulo Correia-de-Sá, Fernanda Almeida
Format:	Article
Language:	English
Published:	MDPI AG 2025-02-01
Subjects:	isopulegol paclitaxel von Frey neuropathy behavioral evaluation pharmacological synergism
Online Access:	https://www.mdpi.com/1424-8247/18/2/256