Nance-Horan-syndrome-like 1b controls mesodermal cell migration by regulating protrusion and actin dynamics during zebrafish gastrulation

Abstract Cell migrations are crucial for embryonic development, wound healing, the immune response, as well as for cancer progression. During mesenchymal cell migration, the Rac1-WAVE-Arp2/3 signalling pathway induces branched actin polymerisation, which protrudes the membrane and allows migration....

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Bibliographic Details
Published in:Communications Biology
Main Authors: Sophie Escot, Yara Hassanein, Amélie Elouin, Jorge Torres-Paz, Lucille Mellottee, Amandine Ignace, Nicolas B. David
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Online Access:https://doi.org/10.1038/s42003-025-07689-6