Decreased TMIGD1 aggravates colitis and intestinal barrier dysfunction via the BANF1-NF-κB pathway in Crohn’s disease

Abstract Background Disrupted intestinal epithelial barrier is one of the major causes of Crohn’s disease (CD). Novel molecular targets for intestinal epithelial barrier are essential to treatment of CD. Transmembrane and immunoglobulin domain-containing protein 1 (TMIGD1) is an adhesion molecule th...

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出版年:	BMC Medicine
主要な著者:	Longyuan Zhou, Liguo Zhu, Xiaomin Wu, Shixian Hu, Shenghong Zhang, Min Ning, Jun Yu, Minhu Chen
フォーマット:	論文
言語:	英語
出版事項:	BMC 2023-08-01
主題:	Crohn’s disease TMIGD1 BANF1 Intestinal epithelial barrier NF-κB pathway
オンライン･アクセス:	https://doi.org/10.1186/s12916-023-02989-2