TolC facilitates the intracellular survival and immunomodulation of Salmonella Typhi in human host cells

Salmonella enterica serovar Typhi (S. Typhi) causes typhoid fever, a systemic infection that affects millions of people worldwide. S. Typhi can invade and survive within host cells, such as intestinal epithelial cells and macrophages, by modulating their immune responses. However, the immunomodulato...

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Bibliographic Details

Published in:	Virulence
Main Authors:	Ashraf Hussain, Eugene Boon Beng Ong, Prabha Balaram, Asma Ismail, Phua Kia Kien
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2024-12-01
Subjects:	Salmonella Typhi multidrug efflux pump AcrAB-TolC invasion of bacteria into host cells mutant induce cytotoxic proinflammatory responses in host cell immunomodulation of macrophages and epithelial cells immunomodulatory ability of pathogens
Online Access:	https://www.tandfonline.com/doi/10.1080/21505594.2024.2395831