Effects of a low-dose IL-2 treatment in HLA-B27 transgenic rat model of spondyloarthritis

Abstract Introduction/Aim HLA-B27/human β2m transgenic rats (B27-rats) develop an inflammatory disorder resembling spondyloarthritis (SpA) with dysregulated IL-10/IL-17 production by regulatory T cells (Treg). Treg plays a major role in controlling pathogenic inflammatory processes. Interleukin 2 (I...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:	Arthritis Research & Therapy
المؤلفون الرئيسيون:	L. M. Araujo, Q. Jouhault, I. Fert, I. Bouiller, G. Chiocchia, M. Breban
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	BMC 2021-07-01
الموضوعات:	Low-dose IL-2 HLA-B27 transgenic rat Regulatory T cells Spondyloarthritis
الوصول للمادة أونلاين:	https://doi.org/10.1186/s13075-021-02559-y

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