PacBio Long Reads Improve Metagenomic Assemblies, Gene Catalogs, and Genome Binning

PacBio long reads sequencing presents several potential advantages for DNA assembly, including being able to provide more complete gene profiling of metagenomic samples. However, lower single-pass accuracy can make gene discovery and assembly for low-abundance organisms difficult. To evaluate the ap...

Full description

Bibliographic Details

Published in:	Frontiers in Genetics
Main Authors:	Haiying Xie, Caiyun Yang, Yamin Sun, Yasuo Igarashi, Tao Jin, Feng Luo
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2020-09-01
Subjects:	hybrid assembly PacBio gene catalog anaerobic digestion genome reconstruction
Online Access:	https://www.frontiersin.org/article/10.3389/fgene.2020.516269/full