Interactions of genetic variations in FAS, GJB2 and PTPRN2 are associated with noise-induced hearing loss: a case-control study in China

Abstract Background This study aimed to screen and validate noise-induced hearing loss (NIHL) associated single nucleotide polymorphisms (SNPs), construct genetic risk prediction models, and evaluate higher-order gene-gene, gene-environment interactions for NIHL in Chinese population. Methods First,...

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出版年:	BMC Medical Genomics
主要な著者:	Shan Wu, Zhidan Wu, Manlian Chen, Xiangbin Zhong, Haoyan Gu, Wenjing Du, Weidong Liu, Li Lang, Junyi Wang
フォーマット:	論文
言語:	英語
出版事項:	BMC 2024-01-01
主題:	Genetic susceptibility Occupational noise-induced hearing loss (NIHL) Single nucleotide polymorphism (SNP) Genetic risk score (GRS) Classification and regression tree (CART)
オンライン･アクセス:	https://doi.org/10.1186/s12920-023-01790-7