Plitidepsin Has a Safe Cardiac Profile: A Comprehensive Analysis

Plitidepsin is a cyclic depsipeptide of marine origin in clinical development in cancer patients. Previously, some depsipeptides have been linked to increased cardiac toxicity. Clinical databases were searched for cardiac adverse events (CAEs) that occurred in clinical trials with the single-agent p...

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Bibliographic Details
Published in:Marine Drugs
Main Authors: Carmen Kahatt, Cinthya Coronado, Pilar Lardelli, Claudia Silvia Corrado, Elena Roy, Vicente Alfaro, Bernardo Miguel-Lillo, Sonia Extremera, Arturo Soto-Matos, Sergio Szyldergemajn
Format: Article
Language:English
Published: MDPI AG 2011-06-01
Subjects:
plitidepsin
cardiac toxicity
single agent
chemotherapy
cancer
Online Access:http://www.mdpi.com/1660-3397/9/6/1007/

Internet

http://www.mdpi.com/1660-3397/9/6/1007/

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