Contrasting roles of KMT2C and KMT2D in breast cancer
Abstract KMT2C and KMT2D are paralogous lysine-methyltransferases that primarily monomethylate lysine residues at enhancer regions promoting an active transcriptional state. KMT2C and KMT2D are frequently mutated in multiple cancer types and in breast cancers mutations collectively occur at frequenc...
| Published in: | Scientific Reports |
|---|---|
| Main Authors: | , , , , |
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-10-01
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| Online Access: | https://doi.org/10.1038/s41598-025-19027-1 |