The genetic interaction map of the human solute carrier superfamily

Abstract Solute carriers (SLCs), the largest superfamily of transporter proteins in humans with about 450 members, control the movement of molecules across membranes. A typical human cell expresses over 200 different SLCs, yet their collective influence on cell phenotypes is not well understood due...

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Bibliographic Details
Published in:Molecular Systems Biology
Main Authors: Gernot Wolf, Philipp Leippe, Svenja Onstein, Ulrich Goldmann, Fabian Frommelt, Shao Thing Teoh, Enrico Girardi, Tabea Wiedmer, Giulio Superti-Furga
Format: Article
Language:English
Published: Springer Nature 2025-05-01
Subjects:
CRISPR Screens
Functional Genomics
Genetic Interactions
Metabolism
Solute Carrier Transporters
Online Access:https://doi.org/10.1038/s44320-025-00105-5

Internet

https://doi.org/10.1038/s44320-025-00105-5

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