DDX21 Promotes PCV3 Replication by Binding to Cap Protein and Inhibiting Interferon Responses

Porcine circovirus type 3 (PCV3) is an emerging pathogen that causes porcine dermatitis, nephropathy syndrome-like symptoms, multisystemic inflammation, and reproductive failure. The PCV3 capsid (Cap) protein interacts with DDX21, which functions mainly through controlling interferon (IFN)-β levels....

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Bibliographic Details

Published in:	Viruses
Main Authors:	Haoyu Sun, Qianhong Dai, Beiyi Zhou, Xiaoyuan Lan, Yonghui Qiu, Qianqian Zhang, Dedong Wang, Yongqiu Cui, Jinshuo Guo, Lei Hou, Jue Liu, Jianwei Zhou
Format:	Article
Language:	English
Published:	MDPI AG 2025-01-01
Subjects:	porcine circovirus type 3 capsid protein DEAD-box RNA helicase 21 viral replication
Online Access:	https://www.mdpi.com/1999-4915/17/2/166