In Vitro Evaluation of Glycoengineered RSV-F in the Human Artificial Lymph Node Reactor

Subunit vaccines often require adjuvants to elicit sustained immune activity. Here, a method is described to evaluate the efficacy of single vaccine candidates in the preclinical stage based on cytokine and gene expression analysis. As a model, the recombinant human respiratory syncytial virus (RSV)...

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Bibliographic Details

Published in:	Bioengineering
Main Authors:	Lars Radke, Grit Sandig, Annika Lubitz, Ulrike Schließer, Hans Henning von Horsten, Veronique Blanchard, Karolin Keil, Volker Sandig, Christoph Giese, Michael Hummel, Stephan Hinderlich, Marcus Frohme
Format:	Article
Language:	English
Published:	MDPI AG 2017-08-01
Subjects:	Glycoengineering fucosylation RSV F-Protein NanoString
Online Access:	https://www.mdpi.com/2306-5354/4/3/70