Coagulofibrinolytic effects of recombinant soluble thrombomodulin in prolonged porcine cardiac arrest

Aim: To evaluate coagulofibrinolytic abnormalities and the effects of ART-123 (recombinant human thrombomodulin alpha) in a porcine model of cardiac arrest and prolonged cardiopulmonary resuscitation (CA/CPR). Methods: Fifteen pigs (n = 5 per group) underwent 8 minutes of no-flow CA followed by 50 m...

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Bibliographic Details

Published in:	Resuscitation Plus
Main Authors:	Boya Zhang, Brendan M. McCracken, Carmen Colmenero Mahmood, Danielle Leander, Nicholas Greer, James A. Cranford, Cindy H. Hsu, Mohamad Hakam Tiba, Robert W. Neumar, Colin F. Greineder
Format:	Article
Language:	English
Published:	Elsevier 2023-12-01
Subjects:	Cardiac arrest Soluble thrombomodulin Porcine model Coagulation Fibrinolysis
Online Access:	http://www.sciencedirect.com/science/article/pii/S2666520423001200