Intra-articular injection of secretome, derived from umbilical cord mesenchymal stem cell, enhances the regeneration process of cartilage in early-stage osteo-arthritis: an animal study

Background and purpose: Mesenchymal stem cells (MSCs), both endogenous and exogenous, enhance chondrocyte proliferation by stimulating collagen type II. Secretome, an MSC derivate, has shown to also provide this mechanism through a paracrine effect. We aimed to evaluate the use of secretome and MSC...

Full description

Bibliographic Details

Published in:	Acta Orthopaedica
Main Authors:	Andri Maruli Tua Lubis, Petrus Aprianto, Jeanne Adiwinata Pawitan, Bambang Pontjo Priosoeryanto, Tri Isyani Tungga Dewi, Achmad Fauzi Kamal
Format:	Article
Language:	English
Published:	Medical Journals Sweden 2023-06-01
Subjects:	Hyaluronic acid mesenchymal stem cells osteoarthritis secretome
Online Access:	https://actaorthop.org/actao/article/view/12359