Enigmatic roles of Vibrio cholerae hemolysin/cytolysin in the bacterial pathogenesis and host-pathogen interactions

ABSTRACT Vibrio cholerae cytolysin (VCC; also known as V. cholerae hemolysin) is a β-barrel pore-forming toxin (β-PFT) secreted by the cholera pathogen V. cholerae. VCC acts to disrupt the selective permeability barrier function of the target cell membranes. Monomeric VCC molecules bind to and form...

Full description

Bibliographic Details

Published in:	Journal of Bacteriology
Main Authors:	Mahendra Singh, Sindhoora Puravankara, Arunika Mukhopadhaya, Kausik Chattopadhyay
Format:	Article
Language:	English
Published:	American Society for Microbiology 2025-08-01
Subjects:	Vibrio cholerae pore-forming toxins Vibrio cholerae cytolysin hemolysins exotoxins
Online Access:	https://journals.asm.org/doi/10.1128/jb.00248-25