Haploinsufficiency of intraflagellar transport protein 172 causes autism-like behavioral phenotypes in mice through BDNF

Introduction: Primary cilia are hair-like solitary organelles growing on most mammalian cells that play fundamental roles in embryonic patterning and organogenesis. Defective cilia often cause a suite of inherited diseases called ciliopathies with multifaceted manifestations. Intraflagellar transpor...

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Bibliographic Details

Published in:	Journal of Advanced Research
Main Authors:	Nanxi Zheng, Shilin Luo, Xin Zhang, Ling Hu, Muzhi Huang, Mingyu Li, Colin McCaig, Yu-Qiang Ding, Bing Lang
Format:	Article
Language:	English
Published:	Elsevier 2025-07-01
Subjects:	Intraflagellar transport protein 172 Primary cilia Autism spectrum disorders Sonic Hedgehog BDNF Bardet Biedl Syndrome
Online Access:	http://www.sciencedirect.com/science/article/pii/S2090123224003825