Bile acids modulate reinstatement of cocaine conditioned place preference and accumbal dopamine dynamics without compromising appetitive learning

Abstract Psychostimulants target the dopamine transporter (DAT) to elicit their psychomotor actions. Bile acids (BAs) can also bind to DAT and reduce behavioral responses to cocaine, suggesting a potential therapeutic application of BAs in psychostimulant use disorder. Here, we investigate the poten...

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Bibliographic Details

Published in:	Scientific Reports
Main Authors:	Daniele Zanella, Nicholas K. Smith, J. Andrew Hardaway, Anna Marie Buchanan, Clarence H. Mullins, Aurelio Galli, Angela M. Carter
Format:	Article
Language:	English
Published:	Nature Portfolio 2023-08-01
Online Access:	https://doi.org/10.1038/s41598-023-40456-3