Optimization of Culture Media and Feeding Strategy for High Titer Production of an Adenoviral Vector in HEK 293 Fed-Batch Culture

Adenoviruses are efficient and safe vectors for delivering target antigens and adenovirus-based vaccines have been used against a wide variety of pathogens, including tuberculosis and COVID-19. Cost-effective and scalable biomanufacturing processes are critical for the commercialization of adenoviru...

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Bibliographic Details

Published in:	Vaccines
Main Authors:	Chun Fang Shen, Anja Rodenbrock, Stephane Lanthier, Elodie Burney, Martin Loignon
Format:	Article
Language:	English
Published:	MDPI AG 2024-05-01
Subjects:	adenovirus HEK 293 cells fed-batch culture feeding strategy
Online Access:	https://www.mdpi.com/2076-393X/12/5/524