Comparison of 18F-T807 and 18F-THK5117 PET in a Mouse Model of Tau Pathology

Positron-emission-tomography (PET) imaging of tau pathology has facilitated development of anti-tau therapies. While members of the arylquinoline and pyridoindole families have been the most frequently used tau radioligands so far, analyses of their comparative performance in vivo are scantly docume...

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Bibliographic Details

Published in:	Frontiers in Aging Neuroscience
Main Authors:	Matthias Brendel, Behrooz H. Yousefi, Tanja Blume, Michael Herz, Carola Focke, Maximilian Deussing, Finn Peters, Simon Lindner, Barbara von Ungern-Sternberg, Alexander Drzezga, Peter Bartenstein, Christian Haass, Nobuyuki Okamura, Jochen Herms, Igor Yakushev, Axel Rominger
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-06-01
Subjects:	tau small animal PET transgenic mice 18F-T807 18F-THK5117
Online Access:	https://www.frontiersin.org/article/10.3389/fnagi.2018.00174/full