Autophagy Disruptions Associated With Altered Optineurin Expression in Extranigral Regions in a Rotenone Model of Parkinson's Disease

The motor features of Parkinson's disease (PD) primarily result from a lesion to the nigrostriatal dopamine system. Numerous non-motor symptoms occur in PD, many of which are postulated to stem from pathology outside of the nigrostriatal dopamine system. Perturbations to protein trafficking, di...

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發表在:	Frontiers in Neuroscience
Main Authors:	John P. Wise, Charles G. Price, Joseph A. Amaro, Jason R. Cannon
格式:	Article
語言:	英语
出版:	Frontiers Media S.A. 2018-05-01
主題:	Parkinson's disease rotenone autophagy optineurin LC3
在線閱讀:	http://journal.frontiersin.org/article/10.3389/fnins.2018.00289/full