Developing survival prediction models in colorectal cancer using epigenome-wide DNA methylation data from whole blood

Abstract While genome-wide association studies are valuable in identifying CRC survival predictors, the benefit of adding blood DNA methylation (blood-DNAm) to clinical features, including the TNM system, remains unclear. In a multi-site population-based patient cohort study of 2116 CRC patients wit...

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Bibliographic Details
Published in:npj Precision Oncology
Main Authors: Ziwen Fan, Dominic Edelmann, Tanwei Yuan, Bruno Christian Köhler, Michael Hoffmeister, Hermann Brenner
Format: Article
Language:English
Published: Nature Portfolio 2024-09-01
Online Access:https://doi.org/10.1038/s41698-024-00689-5