Differential effects of doxorubicin on atrial natriuretic peptide expression in vivo and in vitro

Doxorubicin (Dox) is a potent anti-cancer agent with cardiotoxic side-effects but the mechanism of its cardiotoxicity and its effect on expression of the vasoactive atrial natriuretic peptide (ANP), an important marker for cardiac hypertrophy, are little understood. The present study examined Dox-in...

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Bibliographic Details

Published in:	Biological Research
Main Authors:	ASIM RAHMAN, MAHMOOD ALAM, SUDHA RAO, LIN CAI, CLARK LUTHER T., SAYID SHAFIQ, M.A.Q SIDDIQUI
Format:	Article
Language:	English
Published:	BMC 2001-01-01
Subjects:	Atrial natriuretic peptide gene expression adriamycin heart failure
Online Access:	http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602001000300007