Hypercholesterolemia and the role of lipid metabolism gene CES1 in immune infiltration promote central nervous system relapse in acute myeloid leukemia

BackgroundAlterations in multiple lipid metabolism pathways are associated with cancer progression. However, the relationship between lipid metabolism and central nervous system (CNS) relapse in acute myeloid leukemia (AML) remains unclear.MethodsWe conducted a retrospective analysis of 806 AML case...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:Frontiers in Immunology
المؤلفون الرئيسيون: Wanwan Bao, Yansong Tu, Shan Zhang, Xiaoyan Jiang, Huijun Chen, Huaijun Tu, Jian Li
التنسيق: مقال
اللغة:الإنجليزية
منشور في: Frontiers Media S.A. 2025-07-01
الموضوعات:
central nervous system leukemia
hyperlipidemia
CES1
tumor microenvironment
ESTIMATE
CIBERSORT
الوصول للمادة أونلاين:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1575472/full

الانترنت

https://www.frontiersin.org/articles/10.3389/fimmu.2025.1575472/full

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