Prenatal Progestin Exposure-Mediated Oxytocin Suppression Contributes to Social Deficits in Mouse Offspring

Epidemiological studies have shown that maternal hormone exposure is associated with autism spectrum disorders (ASD). The hormone oxytocin (OXT) is a central nervous neuropeptide that plays an important role in social behaviors as well as ASD etiology, although the detailed mechanism remains largely...

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Bibliographic Details

Published in:	Frontiers in Endocrinology
Main Authors:	Saijun Huang, Jiaying Zeng, Ruoyu Sun, Hong Yu, Haimou Zhang, Xi Su, Paul Yao
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2022-03-01
Subjects:	autism spectrum disorders oxytocin oxidative stress progestin social deficits
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2022.840398/full