The protein architecture of human secretory vesicles reveals differential regulation of signaling molecule secretion by protein kinases.

Secretory vesicles are required for release of chemical messengers to mediate intercellular signaling among human biological systems. It is necessary to define the organization of the protein architecture of the 'human' dense core secretory vesicles (DCSV) to understand mechanisms for secr...

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Bibliographic Details
Published in:PLoS ONE
Main Authors: Steven J Bark, Jill Wegrzyn, Laurent Taupenot, Michael Ziegler, Daniel T O'Connor, Qi Ma, Michael Smoot, Trey Ideker, Vivian Hook
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Online Access:http://europepmc.org/articles/PMC3420874?pdf=render