Quasispecies Changes with Distinctive Point Mutations in the Hepatitis C Virus Internal Ribosome Entry Site (IRES) Derived from PBMCs and Plasma
The 5’ untranslated region (UTR) of the hepatitis C virus (HCV) genome contains the internal ribosome entry site (IRES), a highly conserved RNA structure essential for cap-independent translation of the viral polyprotein. HCV, apart from the liver, is thought to be associated with lymphocyte subpopu...
| Published in: | Advances in Virology |
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| Main Authors: | , , , |
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2018-01-01
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| Online Access: | http://dx.doi.org/10.1155/2018/4835252 |