Transformed Salmonella typhimurium SL7207/pcDNA-CCOL2A1 as an orally administered DNA vaccine

Abstract The use of attenuated bacteria for oral delivery of DNA vaccines is a recent innovation. We designed and constructed the naked plasmid DNA vaccine pcDNA-CCOL2A1, which effectively prevented and treated a rheumatoid arthritis model by inducing immunotolerance. We aimed to ensure a reliable,...

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發表在:	AMB Express
Main Authors:	Juan Long, Yang Zeng, Fei Liang, Nan Liu, Yongzhi Xi, Yuying Sun, Xiao Zhao
格式:	Article
語言:	英语
出版:	SpringerOpen 2024-01-01
主題:	Attenuated Salmonella typhimurium SL7207 DNA vaccine Oral immune Stability Transformed strain SL7207/pcDNA-CCOL2A1
在線閱讀:	https://doi.org/10.1186/s13568-023-01650-8