Systems-Wide Dissection of Organic Acid Assimilation in Pseudomonas aeruginosa Reveals a Novel Path To Underground Metabolism

ABSTRACT The human pathogen Pseudomonas aeruginosa (Pa) is one of the most frequent and severe causes of nosocomial infection. This organism is also a major cause of airway infections in people with cystic fibrosis (CF). Pa is known to have a remarkable metabolic plasticity, allowing it to thrive un...

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Bibliographic Details

Published in:	mBio
Main Authors:	Stephen K. Dolan, Andre Wijaya, Michael Kohlstedt, Lars Gläser, Paul Brear, Rafael Silva-Rocha, Christoph Wittmann, Martin Welch
Format:	Article
Language:	English
Published:	American Society for Microbiology 2022-12-01
Subjects:	Pseudomonas aeruginosa enzyme promiscuity 2-methylcitrate cycle central metabolism propionate metabolism underground metabolism
Online Access:	https://journals.asm.org/doi/10.1128/mbio.02541-22