HrpA anchors meningococci to the dynein motor and affects the balance between apoptosis and pyroptosis

Abstract Background In Neisseria meningitidis the HrpA/HrpB two-partner secretion system (TPS) was implicated in diverse functions including meningococcal competition, biofilm formation, adherence to epithelial cells, intracellular survival and vacuolar escape. These diverse functions could be attri...

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Bibliographic Details

Published in:	Journal of Biomedical Science
Main Authors:	Adelfia Talà, Flora Guerra, Matteo Calcagnile, Roberta Romano, Silvia Caterina Resta, Aurora Paiano, Mario Chiariello, Graziano Pizzolante, Cecilia Bucci, Pietro Alifano
Format:	Article
Language:	English
Published:	BMC 2022-06-01
Subjects:	Host–pathogen interaction Dynein Apoptosis Pyroptosis Cell death Bacteria
Online Access:	https://doi.org/10.1186/s12929-022-00829-8