Enantioselective de novo construction of 3‑oxindoles via organocatalyzed formal [3 + 2] annulation from simple arylamines

Abstract The de novo construction of enantioenriched 3-hydroxyindolenines and 3-oxindoles from easily available starting materials has been highly desired. Herein, an enantioselectively intermolecular direct [3 + 2] annulation of aryl amine with 2,3-diketoesters to construct 3-hydroxyindolenines wit...

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Bibliographic Details

Published in:	Nature Communications
Main Authors:	Yong Wang, Yanyan Li, Haohua Chen, Yu Lan, Chao Pi, Yangjie Wu, Xiuling Cui
Format:	Article
Language:	English
Published:	Nature Portfolio 2024-07-01
Online Access:	https://doi.org/10.1038/s41467-024-50400-2