Prospects for mTOR-mediated functional repair after central nervous system trauma

Recent research has suggested that the growth of central nervous system (CNS) axons during development is mediated through the PI3K/Akt/mammalian target of rapamycin (mTOR) intracellular signalling axis and that suppression of activity in this pathway occurs during maturity as levels of the phosphat...

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Bibliographic Details

Published in:	Neurobiology of Disease
Main Authors:	Martin Berry, Zubair Ahmed, Peter Morgan-Warren, Daniel Fulton, Ann Logan
Format:	Article
Language:	English
Published:	Elsevier 2016-01-01
Subjects:	mTOR Spinal cord injury Axogenesis Axon regeneration Myelination
Online Access:	http://www.sciencedirect.com/science/article/pii/S0969996115300590