Pregnane X Receptor (PXR) Polymorphisms and Cancer Treatment

Pregnane X Receptor (PXR) belongs to the nuclear receptors’ superfamily and mainly functions as a xenobiotic sensor activated by a variety of ligands. PXR is widely expressed in normal and malignant tissues. Drug metabolizing enzymes and transporters are also under PXR’s regulation. Antineoplastic a...

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Bibliographic Details
Published in:Biomolecules
Main Authors: Aikaterini Skandalaki, Panagiotis Sarantis, Stamatios Theocharis
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Subjects:
PXR
polymorphisms
SNP
cancer
treatment
pharmacogenomics
Online Access:https://www.mdpi.com/2218-273X/11/8/1142

Internet

https://www.mdpi.com/2218-273X/11/8/1142

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