MicroRNA-761 suppresses remodeling of nasal mucosa and epithelial–mesenchymal transition in mice with chronic rhinosinusitis through LCN2

Abstract Background Chronic rhinosinusitis (CRS) is characterized by persistent symptomatic inflammation of the nasal passage and sinus mucosa. Various microRNAs (miRs) have been implicated in CRS. Hence, the current study was conducted to explore the effect of microRNA-761 (miR-761) on remodeling o...

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Bibliographic Details

Published in:	Stem Cell Research & Therapy
Main Authors:	Jinzhang Cheng, Junjun Chen, Yin Zhao, Jingpu Yang, Kai Xue, Zonggui Wang
Format:	Article
Language:	English
Published:	BMC 2020-04-01
Subjects:	Chronic rhinosinusitis MicroRNA-761 Lipocalin 2 Nasal mucosa Epithelial–mesenchymal transition
Online Access:	http://link.springer.com/article/10.1186/s13287-020-01598-7