Role of estrogen receptors in the regulation of reactive gliosis

Although estradiol may directly act on neurons to promote neuroprotection in vitro, the participation of other cell types is also necessary to maintain global tissue homeostasis in vivo (Arevalo et al., 2010; Johann and Beyer, 2013; Acaz-Fonseca et al., 2014). Thus, estradiol acts on glial and endot...

Full description

Bibliographic Details

Published in:	Frontiers in Cellular Neuroscience
Main Authors:	Luis Miguel Garcia-Segura, Inigo Azcoitia, George E. Barreto
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2015-02-01
Subjects:	Aromatase Astrocytes Estradiol Microglia Neuroglobin G protein-coupled estrogen receptor-1 nucelar factor kB
Online Access:	http://journal.frontiersin.org/Journal/10.3389/conf.fncel.2015.35.00001/full