Peg-IFNα combined with hepatitis B vaccination contributes to HBsAg seroconversion and improved immune function

Abstract Purpose The purpose of this study was to investigate immunological variations between a group that received the hepatitis B vaccine and a non-vaccine group. We focused on a cohort that achieved HBsAg seroclearance after Peg-IFNα treatment of CHB. Methods We enrolled twenty-eight individuals...

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Bibliographic Details

Published in:	Virology Journal
Main Authors:	Yisi Liu, Shan Ren, Lina Ma, Xiao Lin, Junfeng Lu, Zhenhuan Cao, Sujun Zheng, Zhongjie Hu, Xiaoxue Xu, Xinyue Chen
Format:	Article
Language:	English
Published:	BMC 2024-03-01
Subjects:	Hepatitis B vaccine HBsAg seroconversion Interferon therapy Humoral immunity Functional cure
Online Access:	https://doi.org/10.1186/s12985-024-02344-8