Engineering Adenoviral Vectors with Improved GBM Selectivity

Glioblastoma (GBM) is the most common and aggressive adult brain cancer with an average survival rate of around 15 months in patients receiving standard treatment. Oncolytic adenovirus expressing therapeutic transgenes represent a promising alternative treatment for GBM. Of the many human adenoviral...

Full description

Bibliographic Details
Published in:Viruses
Main Authors: Emily A. Bates, Charlotte Lovatt, Alice R. Plein, James A. Davies, Florian A. Siebzehnrubl, Alan L. Parker
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Subjects:
Online Access:https://www.mdpi.com/1999-4915/15/5/1086