Case Report: Avelumab and ruxolitinib to manage polycythemia vera and secondary metastatic Merkel cell carcinoma: a possible successful combination

We describe a case of second primary malignancy in a 65-year-old patient affected by polycythemia vera treated with the JAK 1/2 inhibitor ruxolitinib. The latter is recognized as a risk factor for the onset of non-melanoma skin cancers in many retrospective and perspective studies, but the concomita...

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Bibliographic Details

Published in:	Frontiers in Oncology
Main Authors:	Chiara Masucci, Mauro Passucci, Emilia Scalzulli, Ida Carmosino, Marcello Capriata, Alessandro Costa, Claudia Ielo, Maurizio Martelli, Massimo Breccia
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-06-01
Subjects:	avelumab Merkel cell carcinoma ruxolitinib polycytemia vera second malignancies
Online Access:	https://www.frontiersin.org/articles/10.3389/fonc.2023.1212638/full