CD146 promotes malignant progression of breast phyllodes tumor through suppressing DCBLD2 degradation and activating the AKT pathway

Abstract Background As a rapid‐progressing tumor, breast malignant phyllodes tumors (PTs) are challenged by the lack of effective therapeutic strategies and suitable prognostic markers. This study aimed to clarify the role and mechanism of CD146 on promoting PTs malignant progression, and to identif...

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Bibliographic Details

Published in:	Cancer Communications
Main Authors:	Jiewen Chen, Qingji Xu, Dan Liu, Xun Li, Mingyan Guo, Xuehui Chen, Jianyou Liao, Rong Lei, Wende Li, Hongyan Huang, Phei Er Saw, Erwei Song, Xiyun Yan, Yan Nie
Format:	Article
Language:	English
Published:	Wiley 2023-11-01
Subjects:	CD146 DCBLD2 phyllodes tumor of breast PI3K/AKT signaling pathway tumor target
Online Access:	https://doi.org/10.1002/cac2.12495