Single nucleotide polymorphisms in MCP-1 and its receptor are associated with the risk of age related macular degeneration.

BACKGROUND: Age-related macular degeneration (AMD) is the leading cause of blindness in the elderly population. We have shown previously that mice deficient in monocyte chemoattractant protein-1 (MCP1/CCL2) or its receptor (CCR2) develop the features of AMD in senescent mice, however, the human gene...

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Bibliographic Details

Published in:	PLoS ONE
Main Authors:	Akshay Anand, Neel Kamal Sharma, Amod Gupta, Sudesh Prabhakar, Suresh Kumar Sharma, Ramandeep Singh, Pawan Kumar Gupta
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2012-01-01
Online Access:	http://europepmc.org/articles/PMC3503775?pdf=render