Increased ROS levels activate AMPK-ULK1-mediated mitophagy to promote pseudorabies virus replication

Abstract Increasing evidence has confirmed that oxidative stress plays a nonnegligible role in the viral pathogenic process. In this study, we investigated the role of reactive oxygen species (ROS) in the replication of pseudorabies virus (PRV). Our data showed that PRV infection initially enhanced...

وصف كامل

التفاصيل البيبلوغرافية
الحاوية / القاعدة:	Veterinary Research
المؤلفون الرئيسيون:	Yuan Zhao, Xiaoyi Qi, Zhenbang Zhu, Wenqiang Wang, Wei Wen, Xiangdong Li
التنسيق:	مقال
اللغة:	الإنجليزية
منشور في:	BMC 2025-07-01
الموضوعات:	Pseudorabies virus reactive oxygen species mitophagy AMPK mitochondria Ca2+ Nrf2
الوصول للمادة أونلاين:	https://doi.org/10.1186/s13567-025-01595-9

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