Insights into durability against resistance from the antibiotic nitrofurantoin
Abstract Nitrofurantoin has shown exceptional durability against resistance over 70 years of use. This longevity stems from factors such as rapid achievement of therapeutic concentrations, multiple physiological targets against bacteria, low risk of horizontal gene transfer, and the need to acquire...
| Published in: | npj Antimicrobials and Resistance |
|---|---|
| Main Authors: | , , , , |
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2024-11-01
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| Online Access: | https://doi.org/10.1038/s44259-024-00056-1 |