Steroidogenesis and androgen/estrogen signaling pathways are altered in in vitro matured testicular tissues of prepubertal mice

Children undergoing cancer treatments are at risk for impaired fertility. Cryopreserved prepubertal testicular biopsies could theoretically be later matured in vitro to produce spermatozoa for assisted reproductive technology. A complete in vitro spermatogenesis has been obtained from mouse prepuber...

Full description

Bibliographic Details

Published in:	eLife
Main Authors:	Laura Moutard, Caroline Goudin, Catherine Jaeger, Céline Duparc, Estelle Louiset, Tony Pereira, François Fraissinet, Marion Delessard, Justine Saulnier, Aurélie Rives-Feraille, Christelle Delalande, Hervé Lefebvre, Nathalie Rives, Ludovic Dumont, Christine Rondanino
Format:	Article
Language:	English
Published:	eLife Sciences Publications Ltd 2023-12-01
Subjects:	androgen estrogen in vitro spermatogenesis Leydig cell mice steroidogenesis
Online Access:	https://elifesciences.org/articles/85562