A Trio of Active Zone Proteins Comprised of RIM-BPs, RIMs, and Munc13s Governs Neurotransmitter Release

Summary: At the presynaptic active zone, action-potential-triggered neurotransmitter release requires that fusion-competent synaptic vesicles are placed next to Ca2+ channels. The active zone resident proteins RIM, RBP, and Munc13 are essential contributors for vesicle priming and Ca2+-channel recru...

Full description

Bibliographic Details

Published in:	Cell Reports
Main Authors:	Marisa M. Brockmann, Fereshteh Zarebidaki, Marcial Camacho, M. Katharina Grauel, Thorsten Trimbuch, Thomas C. Südhof, Christian Rosenmund
Format:	Article
Language:	English
Published:	Elsevier 2020-08-01
Subjects:	synaptic transmission active zone presynaptic scaffold proteins release probability RIM-RBP-Munc13 complex neurotransmitter release
Online Access:	http://www.sciencedirect.com/science/article/pii/S2211124720309414