Gene expression signature predicts radiation sensitivity in cell lines using the integral of dose–response curve

Abstract Background Although substantial efforts have been made to build molecular biomarkers to predict radiation sensitivity, the ability to accurately stratify the patients is still limited. In this study, we aim to leverage large-scale radiogenomics datasets to build genomic predictors of radiat...

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Bibliographic Details

Published in:	BMC Cancer
Main Authors:	Alona Kolnohuz, Leyla Ebrahimpour, Sevinj Yolchuyeva, Venkata S. K. Manem
Format:	Article
Language:	English
Published:	BMC 2024-01-01
Subjects:	Radiation sensitivity Radiotherapy Dose-response Gene expression signature OMICS Radiobiological model
Online Access:	https://doi.org/10.1186/s12885-023-11634-3