Cbl-b negatively regulates TLR/MyD88-mediated anti-Toxoplasma gondii immunity

ABSTRACT Toxoplasma gondii is an important intracellular protozoan, which needs to exploit host nutrition for successful parasitism. We previously reported that Casitas B-lineage lymphoma-b (Cbl-b) was screened as a host dependency factor of T. gondii by using lentiviral CRISPR-Cas9-single guide RNA...

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Bibliographic Details
Published in:Microbiology Spectrum
Main Authors: Haixia Wei, Shuizhen Wu, Liying Mai, Lili Yang, Weihao Zou, Hongjuan Peng
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Subjects:
Toxoplasma gondii
TLRs/MyD88
Cbl-b
ubiquitination
Online Access:https://journals.asm.org/doi/10.1128/spectrum.00074-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.00074-23

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