Novel insights into cancer stem cells targeting: CAR-T therapy and epigenetic drugs as new pillars in cancer treatment

Cancer stem cells (CSCs) represent the most aggressive subpopulation present in the tumor bulk retaining invasive capabilities, metastatic potential and high expression levels of drug efflux pumps responsible for therapy resistance. Cancer is still an incurable disease due to the inefficacy of stand...

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Bibliographic Details

Published in:	Frontiers in Molecular Medicine
Main Authors:	Veronica Veschi, Alice Turdo, Giorgio Stassi
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2023-05-01
Subjects:	CAR-T cell therapy CAR-NK epigenetic inhibitors cancer stem cells epigenetic drugs
Online Access:	https://www.frontiersin.org/articles/10.3389/fmmed.2023.1120090/full