An Integrative Pharmacology-Based Pattern to Uncover the Pharmacological Mechanism of Ginsenoside H Dripping Pills in the Treatment of Depression

Objectives: To evaluate the pharmacodynamical effects and pharmacological mechanism of Ginsenoside H dripping pills (GH) in chronic unpredictable mild stress (CUMS) model rats.Methods: First, the CUMS-induced rat model was established to assess the anti-depressant effects of GH (28, 56, and 112 mg/k...

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Bibliographic Details

Published in:	Frontiers in Pharmacology
Main Authors:	Libin Zhao, Rui Guo, Ningning Cao, Yingxian Lin, Wenjing Yang, Shuai Pei, Xiaowei Ma, Yu Zhang, Yingpeng Li, Zhaohui Song, Wuxun Du, Xuefeng Xiao, Changxiao Liu
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-02-01
Subjects:	ginsenoside H dripping pills depression network pharmacology chronic unpredictable mild stress cAMP signaling pathway
Online Access:	https://www.frontiersin.org/articles/10.3389/fphar.2020.590457/full