Comparative characterization of bronchial and nasal mucus reveals key determinants of influenza A virus inhibition

ABSTRACT Differentiated primary human respiratory epithelial cells grown at air-liquid interface have become a widely used cell culture model of the human conducting airways. These cultures contain secretory cells such as goblet and club cells, which produce and secrete mucus. Here, we characterize...

Full description

Bibliographic Details

Published in:	mSphere
Main Authors:	Marie O. Pohl, Kalliopi Violaki, Lu Liu, Elisabeth Gaggioli, Irina Glas, Josephine von Kempis, Carina Messerli, Chia-wei Lin, Céline Terrettaz, Shannon C. David, Frank W. Charlton, Ghislain Motos, Nir Bluvshtein, Aline Schaub, Liviana K. Klein, Beiping Luo, Nicole C. Leemann, Markus Ammann, Walter Hugentobler, Ulrich K. Krieger, Thomas Peter, Tamar Kohn, Athanasios Nenes, Silke Stertz
Format:	Article
Language:	English
Published:	American Society for Microbiology 2025-09-01
Subjects:	respiratory mucus influenza A virus neuraminidase
Online Access:	https://journals.asm.org/doi/10.1128/msphere.00365-25